Glycopyrrolate (Generic Robinul)

Glycopyrrolate (Generic Robinul) 0.2mg/ml 20ml

Glycopyrrolate Injection (Generic Robinul) 20ml (0.2mg/ml)

Glycopyrrolate is used to reduce secretions in the airway, mouth, throat and stomach.

CLINICAL PHARMACOLOGY:

Glycopyrrolate, like other anticholinergic (antimuscarinic) agents, inhibits the action of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. These peripheral cholinergic receptors are present in the autonomic effector cells of smooth muscle, cardiac muscle, the sinoatrial node, the atrioventricular node, exocrine glands and, to a limited degree, in the autonomic ganglia. Thus, it diminishes the volume and free acidity of gastric secretions and controls excessive pharyngeal, tracheal, and bronchial secretions.

Glycopyrrolate antagonizes muscarinic symptoms (e.g., bronchorrhea, bronchospasm, bradycardia, and intestinal hypermotility) induced by cholinergic drugs such as the anticholinesterases.