Buy Azium injection ONLINE

Azium  injection (dexamethasone) Solution is a synthetic analogue of prednisolone, having similar but more potent anti-inflammatory therapeutic action and diversified hormonal and metabolic effects. Modification of the basic corticoid structure as achieved in AZIUM Solution offers enhanced anti-inflammatory effect compared to older corticosteroids. The dosage of AZIUM Solution required is markedly lower than that of prednisone and prednisolone.

AZIUM Solution is not species-specific; however, the veterinarian should read the sections on INDICATIONS, DOSAGE, SIDE EFFECTS, CONTRAINDICATIONS, PRECAUTIONS, and WARNINGS before this drug is used.

AZIUM Solution is intended for intravenous or intramuscular administration. Each mL contains 2 mg dexamethasone, 500 mg polyethylene glycol 400, 9 mg benzyl alcohol, 1.8 mg methylparaben and 0.2 mg propylparaben as preservatives, 4.75% alcohol, HCl to adjust pH to approximately 4.9, and water for injection q.s.

Brand Name: Azium, Voren

Available in 0.25 mg, 0.50 mg, 0.75 mg, 1 mg, 1.5 mg, 2 mg, 4 mg and 6 mg tablets; oral solution; several eye drop formulations

Uses of this Medication

Dexamethasone is a member of the glucocorticoid class of hormones. This means they are steroids but, unlike the anabolic steroids that we hear about regarding sports medicine, these are catabolic steroids.

In most cases, we do not use glucocorticoids for their influences on glucose and protein metabolism; we use them because in higher doses they are broadly anti-inflammatory. Their uses fit into several groups:

• Anti-inflammatory – especially for joint pain and itchy skin.
• Immune-suppression – treatment of conditions where the immune system is destructively hyperactive. Higher doses are required to actually suppress the immune system.
• Cancer chemotherapy – although usually prednisolone, another steroid, is favored for this use.
• Central nervous system disorders – usually after a disk episode to relieve swelling in the spinal cord.
• Blood calcium reduction – in medical conditions where blood calcium is dangerously high and treatment is needed to reduce levels to normal.
• Dexamethasone also has some use in pregnancy termination in dogs.

Side Effects of Azium injection

The reason for this is that body will perceive these hormones and not produce any of its own. In time, the adrenal glands will atrophy so that when the medication is discontinued, the patient will be unable to respond to any stressful situation. A blood sugar crisis can result. By using the medication every other day, this allows the body’s own adrenal glands to remain active.

Glucocorticoid hormone use can be irritating or even ulcerating to the stomach or intestine at higher doses.

Long-term steroid use strongly predisposes a patient to latent urinary tract infection.

Interactions with other Drugs

Glucocorticoid hormones should not be used in combination with medications of the NSAID class (i.e. aspirin, carprofen, meloxicam, etc.) as the combination of these medications could lead to bleeding in the stomach or intestine. Ulceration could occur.

Macrolide antibiotics (such as clarithromycin or erythromycin) can increase dexamethasone blood levels.  Use of the antifungal ketoconazole can have a similar interaction.

Diuretics that work by reducing blood potassium levels can create significantly low blood potassium levels when combined with dexamethasone.

Concerns and Cautions

Dexamethasone is considered to be a long-acting steroid, meaning that a dose lasts about two or two-and-a-half days. For this reason an every other day schedule is excessive for dexamethasone; every third day or less is the goal for dexamethasone.

The same salt retention that accounts for excessive thirst and urination may also be a problem for heart failure patients or other patients who require sodium restriction.