Glucosamine 200mg/ml 100ml

Glucosamine 200mg/ml 100ml

:  Anti-Inflammatory, Anti-Arthritic & Chondroprotective Agent for IV Use in Horses.

COMPOSITION:  Contains:  GLUCOSAMINE HYDROCHLORIDE 200 mg/ml

ACTIONS:  Glucosamine is utilized in the production of glycosaminoglycans (GAGs) which then combine with hyaluronic acid (HA) to form large proteoglycans in the matrix of cartilage.  As such, glucosamine is a fundamental molecule for the synthesis and the structure of cartilage.  A growing body of evidence supports the pain relieving and potentially chondroprotective properties of glucosamine.  Notably, glucosamine prevents the degradation of cartilage proteoglycans in vitro and also regulates the production of proteoglycan by chondrocytes.  Glucosamine has also been shown in vitro to protect against the inhibition of proteoglycan production in chondrocytes caused by methylprednisolone.
Oral administration of glucosamine and chondroitin sulfate has demonstrated positive effects on equine osteoarthritis and intravenous administration of glucosamine more rapidly produces significantly higher serum and synovial fluid glucosamine levels.  During one twelve hour study period, intravenous administration in horses created maximum glucosamine levels 50 times higher in the serum and over 20 times higher in the synovial (joint) fluid than via oral administration of the same glucosamine HCl dose.
In Australian trials of GLUCOSAMINE HYDROCHLORIDE 200 mg/ml, veterinarians reported “Good” to “Very Good” response in 67.5% of the osteoarthritic horses treated (20mL IV daily for 5 – 10 days in most cases).  Positive responses have included improved action and race performance and reduced lameness and joint effusion.  Pentosan polysulfate, as contained in Racehorse Meds PENTOSAN INJECTION and PENTOSAN GOLD  is known to stimulate cartilage healing… a process which utilizes glucosamine for production of GAGs and HA.